In This Article

Need a quick escape with a mix of charm and adventure? These getaways in Missouri bring cozy towns, lake retreats, and scenic spots perfect for a refreshing break.

Highlights:

  • Romantic strolls in historic St. Charles
  • Lakeside adventures in Lake of the Ozarks
  • Charming getaways in Branson
  • Wine country weekends in Hermann
  • Cozy B&B stays in Weston

Unique Weekend Getaways in Missouri:

1. Camden on the Lake, Missouri

Rating: ★★★★★

Camden on the Lake, Missouri

© Camden on the Lake, Missouri

Location:

Lake Ozark, MO

Highlights:

Need a fun and relaxing lakeside escape? Camden on the Lake Resort, Spa, & Yacht Club is your go-to for live music, spa indulgence, and water adventures—all set on beautiful Lake Ozark.

Recommended For:

Couples, spa lovers, and active travelers looking for a waterfront getaway with luxury touches and lakefront thrills.

What I Love: ♥

The swim-up bar, spa services, and access to boating and parasailing make this a perfect mix of serenity and adventure.
  • Stay in luxurious rooms and suites with kitchenettes, offering comfort, convenience, and views of the water.
  • Dine at the elegant H. Toad’s Bar and Grill or sip cocktails at the swim-up bar while enjoying live music by the pool.
  • Unwind with soothing treatments at the full-service spa, ideal for a romantic or rejuvenating weekend.
  • Play with boating, parasailing, and wave runner rentals right from the resort—perfect for active lake days.
  • Golfers will appreciate the access to several nearby courses to round out their weekend itinerary.

Address:

Camden on the Lake Resort, Spa, & Yacht Club
2359 Bittersweet Rd, Lake Ozark, MO 65049
Phone: 573-365-5620

2. Affordable Hotel Frederick - 1 hour 40 minutes from Kansas City

Affordable Hotel Frederick - 1 hour 40 minutes from Kansas City

© Hotel Frederick

Location:

Boonville, MO

Highlights:

If you love history, charm, and a good dose of elegance, we highly recommend a stay at Hotel Frederick. This beautifully restored 1905 property in downtown Boonville offers vintage character, artful décor, and luxurious touches that make every stay feel special.

Recommended For:

Couples, history lovers, and travelers seeking a romantic or culturally rich stay in a small-town Missouri setting.

What I Love: ♥

The blend of historic architecture and antique furnishings with pampering details like rain showers, robes, and cozy sheets.
  • Stay in one of the 25 individually designed rooms and suites, some featuring air jet tubs, rain showers, and sitting areas.
  • Appreciate the historic artwork, maps, and antiques thoughtfully displayed throughout the hotel for a sense of place and past.
  • Dine at The Fred restaurant, which serves flavorful lunch and dinner options in a cozy, art-filled space.
  • Relax in the on-site lounge, where you can enjoy a curated selection of appetizers and sandwiches with a drink in hand.

Address:

Hotel Frederick, 501 East High Street, Boonville, MO 65233
Phone: 888-437-3321

Romantic Weekend Getaways in Missouri:

3. D'Monaco - 3 hours 45 minutes from Kansas City

D'Monaco - 3 hours 45 minutes from Kansas City

© D'Monaco

Location:

Ridgedale, MO

Highlights:

If you’re dreaming of a serene escape with jaw-dropping lake and mountain views, D’Monaco Villas delivers in every way. Tucked along Table Rock Lake, this intimate resort is all about relaxation, scenic beauty, and upscale comfort.

Recommended For:

Couples, families, and anyone seeking a peaceful Ozarks retreat with luxury touches and room to spread out.

What I Love: ♥

Spacious villas with panoramic windows, a private dock for lake fun, and a pool with a swim-up bar—pure vacation bliss.
  • Stay in one of six villa layouts, perfect for romantic getaways or family vacations, each designed with comfort and elegance in mind.
  • Relax with sweeping views of Table Rock Lake and the Ozark Mountains through floor-to-ceiling windows or from your private outdoor area.
  • Cook your own meals in a fully equipped kitchen or explore nearby dining spots if you prefer to eat out.
  • Unwind poolside at the resort’s swim-up bar or set off from the private dock for a day of lake fun.
  • Play a few rounds at one of the many excellent golf courses nearby, a perfect complement to the restful pace of your stay.

Address:

D’Monaco Villas, 4125 State Highway 86, Ridgedale, MO 65739
Phone: 888-336-6622

4. Margaritaville Lake Resort

Margaritaville Lake Resort

© Margaritaville Lake Resort

Location:

Osage Beach, MO

Highlights:

Looking for a resort where the vibes are chill, the views are epic, and the activities never stop? Margaritaville Lake Resort is the perfect escape. With 420 acres on the Lake of the Ozarks, it's ideal for couples and families who want fun, relaxation, and lakeside luxury.

Recommended For:

Couples, families, water lovers, and anyone who wants a laid-back lake vacation with resort-level perks.

What I Love: ♥

700 accommodations to suit every style, a full-service marina, indoor waterpark, and a totally relaxed, island-inspired vibe.
  • Stay in one of 700 rooms spread across five buildings, or go big with a six-bedroom house perfect for family gatherings.
  • Play at Timber Falls Indoor Water Park—a family favorite featuring exciting waterslides and a three-story treehouse.
  • Unwind with a treatment at the on-site spa and salon, or soak up the sun by the lake.
  • Explore the water with rentals and activities from the full-service marina.
  • Dine at multiple on-site restaurants serving everything from casual bites to island-style fare.

Address:

Margaritaville Lake Resort, 494 TanTarA Dr, Osage Beach MO 65065
Phone: 800-826-8272

Plan Your Trip