Adjacent to the Florence National Cemetery is the site of the Civil War prison known as the Florence Stockade. Only a historical marker remains of the location also known as The Stockade and the Confederate States Military Prison that housed nearly 18,000 Union soldiers from September 1864 through February 1865. Approximately 2,800 soldiers died in captivity, with many buried as unknown soldiers in the cemetery. Visitors to the site, which is listed on the National Register of Historic Places and part of the City of Florence Trail System, will find a guided walking trail and commemorative gazebo highlighting the history.

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