Looking for riverfront charm, historic sights, and scenic beauty? I think you should definitely visit Cape Girardeau. I’ve wandered its downtown more than once, and every time I find something new—from murals that tell local stories to cozy cafés and riverfront views that just make you pause. You’ll find this southeast Missouri gem nestled along the Mississippi River, blending small-town hospitality with rich history and outdoor fun. If you're like me, you'll love the way everything feels walkable, relaxed, and full of pleasant surprises.

Best Time to Visit

From my experience, the best time to explore Cape Girardeau is April through October. Spring and fall bring that perfect mix of sunshine and fresh air, which makes strolling the historic streets and attending riverfront festivals feel just right. I’ve enjoyed hiking the trails and visiting the gardens during this stretch—you’ll want your camera ready.

How to Get There

  • By Car: I’ve made the drive down I-55 a few times—it’s super simple. You’re looking at about 2 hours from St. Louis or 3 hours from Memphis. It’s an easy road trip with beautiful scenery as you get close to town.
  • By Air: If flying works better for you, I recommend checking out Cape Girardeau Regional Airport. I’ve flown in from Nashville, and it’s a smooth connection that puts you just minutes from downtown.
  • By Bus: I’ve seen friends arrive via Jefferson Lines. If you’re traveling light and want a no-stress way to get there, it’s definitely a solid option.

Where to Stay

  • Courtyard by Marriott Cape Girardeau Downtown – I stayed here on my first trip, and it couldn’t have been more convenient. You’ll be steps from great food, historic spots, and the riverwalk—it’s modern, clean, and perfectly placed.
  • Drury Plaza Hotel Cape Girardeau Conference Center – I’ve recommended this place to family, and they always rave about the free breakfast and evening snacks. If you’re like me and appreciate those little comforts, this is a great pick.
  • White Cliff Manor Bed & Breakfast – When I wanted something more charming and quiet, I stayed here. It’s in nearby Brazeau and offers beautiful river views, antique décor, and that peaceful B&B vibe you can’t get anywhere else.

Top Attractions in Cape Girardeau, Missouri

Trail of Tears State Park

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Trail of Tears State Park - Walk along historic paths and reflect on meaningful sights from America’s past.                                    

West Park Mall

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West Park Mall - Shop favorite brands and explore food options on an easy indoor outing.                                    

Fort D Historic Site

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Fort D Historic Site - Visit Civil War remains and discover fascinating military stuff.                                    

Old St. Vincent's Catholic Church

Old St. Vincent's Catholic Church

Old St. Vincent's Catholic Church - Admire Gothic architecture and explore peaceful interiors on a quiet historical stop.                                    

Levi's Adventure Trail

Levi's Adventure Trail

Levi's Adventure Trail - Go climbing and explore playgrounds with the kids.                                    

36 Restaurant and Bar

36 Restaurant and Bar

36 Restaurant and Bar - Savor fine dishes and admire stylish décor on a romantic evening out.                                    

In Summary...

(and if you want to revisit my photo journey)