Located in the historical Moravian region of the Czech Republic, Brno is another city that tends to fly under the radar, but most people who come here can't help but fall in love with its magnificent modernist architecture, its cozy cafe culture, and its hip, laid-back atmosphere. Most of the biggest attractions are located in the walkable historic city center, including the Špilberk Castle, the gorgeous Petrov Cathedral, and the 17th century Capuchin Monastery. There are also some excellent museums, including the Mendel Museum of Genetics and the Moravian Museum, the second largest museum in the country.