- Please support our journalism through affiliate links. Affiliate Disclosure
Review:
San Luis Obispo is centrally located in California between Los Angeles and San Francisco and is known as one of the “happiest places in America.” The small town is seated between the Pacific Ocean and inland mountains and offers thousands of acres of protected outdoor space, a stellar wine growing region, and a walkable and vibrant downtown. San Luis Obispo is home to California Polytechnic State University, known as Cal Poly, it’s one of the top-ranked universities in America. Visit the 1792 Mission San Luis Obispo Tolosa. The mission was the fifth in California founded by Father Junipero Serra and has been beautifully restored. Downtown’s shopping and dining district is across the mission plaza.
Plan Your Trip
Get Ready to Go!
- Search flights and stays nearby.
- Book your tour or local activity.
- Book your car rental.
Need some more help?
Read our Reservations & Travel Planning Tips guide.