The Cathedral Basilica of the Immaculate Conception is a Roman Catholic cathedral located on South Claiborne Street. As early as 1703, a cathedral parish was founded in Mobile that was known as Notre Dame de la Mobile.

There were several small churches that were built over the ensuing years and the current cathedral was built between 1835 and 1850. During the 1870s, the portico with its eight huge columns was added and the two towers were completed in 1884. The cathedral has been restored several times, including in 1954 and during the decade of the 2000s. The stained glass windows are one of the major attractions of the cathedral: they were made in Munich, Germany, and installed between 1890 and 1910.

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