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The Great River Road is a collection of local and state roads that collectively follow the length of the Mississippi River, traveling through 10 states between Minnesota and Louisiana. The quaint road is home to some of Missouri's most renowned historic attractions, including the registered National Natural Landmark Mark Twain Cave Complex, featured in five of the author's novels. A number of state historic sites are accessible from the road, including the Paleoindian-connected Mastodon State Historic Site, which tells the tale of the Clovis culture, and the National Historic Landmark Bolduc House Museum, constructed in 1792 and preserved as a living history museum. The Rosemary Berkel and Harry L. Crisp II Museum showcases the history of southeast Missouri's culture and industry, while Historic Main Street St. Charles has been named as the Williamsburg of the West by Southern Living. Other attractions include historic 20th-century chocolatier Bankhead Chocolates, Cuivre River State Park, and the award-winning Chaumette Vineyards and Winery.
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