Panama is a vibrant and remarkable destination for both weekend getaways and week-long vacations. Not sure where to start your hunt for the perfect accommodations to book a stay at? We’ve got 25 of the most popular and celebrated hotels in Panama for you to check out down below. CDC information for travelers. Hours/availability may have changed.

1.Red Frog Beach Island Resort

Red Frog Beach Island Resort
© Red Frog Beach Island Resort

Nature lovers and beach lovers alike will love a stay at the Red Frog Beach Island Resort. This resort is nestled within the enchanting archipelago of the Bocas and brings a truly Caribbean experience to the table. Red Frog offers top rated accommodations, amazing beaches, once-in-a-lifetime tours and sweeping vistas of Panama’s natural beauty. Guests of the Red Frog Beach Island Resort will have access to a spectacular nature preserve, the sights and sounds of the tropics, and a breathtaking island eco-system home to exotic birds and even the occasional sloth. Some of the accommodations that guests can choose from include the Jungle Lodge, which is perfect for guests who want a remote and secluded room, and villas with up to 6 bedrooms.

Isla Bastimentos, Archipelago de Bocas del Toro, Isla Bastimentos, Panama, Phone: 507-836-5501

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2.Islas Secas Reserve and Lodge

Islas Secas Reserve and Lodge
© Islas Secas Reserve and Lodge

Islas Secas Reserve and Lodge is a newly-opened world-class resort within the Islas Secas, or Dry Islands, archipelago along Panama's Pacific Ocean coastline near the Gulf of Chiriqui. The eco-friendly resort was originally constructed by American entrepreneur Michael Klein, the islands' previous owner, and has been completely overhauled for 2019 after five years of major renovation. Today, the resort is home to nine secluded villas, which offer private beachfront access and amenities such as indoor-outdoor showers, fully-stocked mini bars, and complimentary wireless internet. Gourmet a la carte dining is offered at The Terraza, which is helmed by executive chef Alex Hey Rojas. Other resort amenities include a Hemingway-style bar and lounge and a game room and library. Resort visitors can explore the UNESCO World Heritage Site-designated Coiba National Park or embark on world-class diving, fishing, and snorkeling expeditions. Phone: 800-377-8877

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3.Tranquilo Bay Eco Adventure Lodge

Tranquilo Bay Eco Adventure Lodge
© Tranquilo Bay Eco Adventure Lodge

Fall in love with Panama at the Tranquilo Bay Eco Adventure Lodge. In fact, you won’t just fall in love with Panama at Tranquilo Bay. You’ll fall in love with exploring and adventuring, too. Perfect for eager explorers and curious vacationers, Tranquilo Bay offers a rainforest adventure unlike any other in the heart of Isla Bastimentos, Panama. This popular eco adventure location offers access to beautiful beaches, kayaking, hiking, snorkeling and more. Spot a 3-toed baby sloth clinging to its mother in the canopy above or keep an eye out for a troop of capuchin monkeys swinging from tree to tree. You can even go sports fishing or explore the rainforest jungle in a surreal and vivid way by joining one of the rainforest hikes. There’s no shortage of recreation and fun here, that’s for sure.

Isla Bastimentos, Panama, Phone: 713-589-6952

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4.Azul Paradise

Azul Paradise
© Azul Paradise

Situated on one of the outer islands of the beautiful Bocas del Toro, Azul Paradise lives up to its name entirely by being home to one of the most beautiful beaches in the Bocas. Visitors headed to Azul Paradise will get whisked away into the seclusion and unimaginable beauty that the hotel has to offer where white sand beaches stretch on for miles and waters are inviting. The calm waters surrounding the hotel are perfect for a relaxing dip and are also home to a whole host of marine life from small fish, colorful jelly fish and a semi-permanent population of magnificent Bottlenose dolphins.

Lot #1 Coconut Coast Isla Bastimentos, Bocas Del Toro, Panama, Phone: 507-6949-3848

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5.Panama Hotels: Bambuda Lodge

Panama Hotels: Bambuda Lodge
© Bambuda Lodge

There’s no doubt that a trip to the best beaches of Panama can cost a pretty penny. Luckily, the Bambuda Lodge allows discerning travelers with a tighter budget experience the beauty of Panama at a more affordable rate. Bambuda is the only hotel in the Bocas that enjoys a waterfront location. Aside from that, the hostel also has a huge fresh water pool for visitors to capitalize on as well as a 150-foot waterslide that travels from the bar straight to the ocean. The chilled out atmosphere is bound to bring the good vibrations to ever traveler that walks into its grounds. Meanwhile, the ocean is a lush colorful underwater jungle just waiting to be explored.

Solarte, Bocas del Toro, Panama, Phone: 507-6962-4644

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6.Panama Resorts: Casa Cayuco

Panama Resorts: Casa Cayuco
© Casa Cayuco

Paradise awaits at Casa Cayuco, an eco-adventure resort that that is completely off the grid and yet still uniquely luxurious. Hidden in the wilds of the Bocas, Casa Cayuco is committed to providing travelers and the wildlife alike with a safe space to co-exist and enjoy an incredible time in Panama. With electricity coming from the sun and water coming from the rain (don’t worry, it’s purified!), the next awesome and eco-friendly feature of the resort are its stand-alone cabins that are open-air and come with a lot of space. The covered porches provide visitors with some shade to enjoy the tropical surroundings and are also a great place to enjoy the meals and snacks that come with every stay.

Punta Vieja, Isla Bastimentos, Bocas del Toro, Panama, Phone: 313-355-6692

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7.Panama Hotels: Casa Ramirez Hotel Boutique Panama

Panama Hotels: Casa Ramirez Hotel Boutique Panama
© Courtesy of Cristian Kerekes -

Looking for a place to stay in Panama City? Make your holiday one for the books by booking a stay at the Casa Ramirez Hotel Boutique. Welcoming, eclectic and distinctly Central American, the Casa Ramirez offers guests a plunge pool, a relaxing sauna, fantastic outdoor amenities and lively common areas to spend time in. Guest rooms are homey and are furnished with flat-screen televisions, a mini-fridge, a mini-bar, and lovely tile and wood details that add character to the accommodations. We can’t forget to mention that the hotel is in a great location and is just a 20-minute drive from attractions like the Presidential Place, the Bridge of the Americas and the Maracana Stadium.

Via Cincuentenario, House 511, Altos Del Golf, Panama City, Panama, Phone: 507-397-0340

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8.Panama Hotels: Casa Sucre Boutique Hotel

Panama Hotels: Casa Sucre Boutique Hotel
© Casa Sucre Boutique Hotel

Adorably quaint and charming, the Casa Sucre Boutique Hotel is housed in a renovated 1873 building that was once a three-apartment, five-bedroom guest house. Found in the center of Casco Viejo, a historic neighborhood in San Felipe City, Casa Sucre sends guests back in time 150 years through its enchanting interiors and suites. Long term guests may want to choose between the Loft, Crema or Rojo apartments, while short term guests will love a stay at any one of the five bedrooms available. The limited number of rooms ensures a private and cozy stay and more opportunities to get to know other travelers staying at the hotel.

Calle 8 y Avenue B, Casco Viejo, Panama, Phone: 507-6982-2504

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9.Eurostars Panama City

Eurostars Panama City
© Eurostars Panama City

Conveniently located in the center of Panama City’s business district, the Eurostars Panama City is a 5-star hotel that exudes elegance and style worthy of a top hotel. Built in 2011, the Eurostar is housed in a modern building and has 300 rooms to offer. The best rooms in the hotel are undoubtedly its two Presidential suites. Guests can enjoy unbeatable views of the city skylines and make the most of luxury amenities such as a gym, a spa, a rooftop swimming pool and a PC corner for business travelers. If you can’t decide on where to eat in the city, we highly recommend a visit to the hotel’s restaurant, which has great views of the city, especially at night.

Calle Ricardo Arias, Bellavista Via Espancia, Panama City, Panama, Phone: 440-843-508-0328

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10.Hard Rock Hotel Panama Megapolis

Hard Rock Hotel Panama Megapolis
© Hard Rock Hotel Panama Megapolis

Ready to vacation like a rock star? Head to the Hard Rock Hotel Panama Megapolis to kickstart a Panama vacation unlike any other. Rock Hard at one of the hottest hotels in Latin America, where every stay makes you feel like you’re living the life of a VIP. The hotel is housed in an awesome 66-story building that’s just a 15-minute drive from the Panama Canal and offers you everything that you could ever need in a luxurious stay whether it’s dining, nightlife or unbeatable entertainment. Take your pick from a variety of stylish rooms and suites with features like a fully stocked mini-bar and ocean view balconies.

Boulevard El Hayek, Panama City, Panama, Phone: 507-294-4000

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11.Panama Hotels: Hilton Panama

Panama Hotels: Hilton Panama
© Hilton Panama

A stay at the Hilton Panama is like a trip to a stunning oasis. Armed with exceptionally clean and stylish rooms, the Hilton does everything possible to make sure that you have a great vacation and an incredible place to stay. Location wise, the Hilton is spectacular. It’s just 2 blocks away from the city’s financial district, a short drive from the Tocumen Airport, and also a leisurely walk to the popular restaurants and shops of Panama City’s downtown area. Make sure to pay a visit to the hotel’s Eforea Spa for amazing treatments and aqua therapy and Ruth’s Christ Steakhouse for a fantastic meal. Not enough for you? The Hilton also has a 24-hour fitness center, a steam room and sauna, as well as a heated outdoor pool, whirlpool and sundeck.

Balabao Avenida and Aquilino de la Guardia, Panama City, Panama, Phone: 507-280-8000

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12.Panama Hotels: Hotel DeVille

Panama Hotels: Hotel DeVille
© Hotel DeVille

Ready to travel back in time to Panama’s most romantic period? If yes, then you’re definitely going to want to book at a stay at the DeVille Hotel. The Hotel DeVille is a spectacularly beautiful boutique hotel that is inspired by French interiors and hospitality. The rooms at the hotel are comfortable and larger than usual. Cozy and quiet, the rooms are also fitted with all the modern amenities a guest could need like cable TVs, minibars, Wi-Fi, coffee makers and safety deposit boxes. The Hotel DeVille is also centrally located, making it a great choice for businessmen, while its smaller size ensures personalized service that’s hard to find these days.

Calle 50 y Beatriz M. de Cabal, Panama City, Panama, Phone: 507-206-3100

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13.Panama Hotels: La Concordia Boutique Hotel

Panama Hotels: La Concordia Boutique Hotel
© La Concordia Boutique Hotel

Distinct, distinguished and a beacon of style and hospitality, the La Concordia Boutique Hotel sits on a busy corner of Avenida Central in the center of the San Felipe and Santa Ana neighborhoods. The surrounding area is a great place for guests to explore to get a glimpse into the everyday life of locals in Panama. From magnificent churches to busy butcher shops to the houses of the city’s elite, there’s a lot to take in in the immediate vicinity of the hotel. There are three room variations to choose from at the La Concordia: the Santa Ana, the San Felipe Jr. Suite, and corner suites. Each room is tastefully decorated and tailored with colorful accents, large windows, high ceilings and a bespoke style to provide guests with a tasteful experience.

Ave Central y Calle A y Calle B, Santa Ana, Panama City, Panama, Phone: 507-300-1125

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14.Las Clementinas

Las Clementinas
© Las Clementinas

What do you have to look forward to when you book a stay at the Las Clementinas? Charming apartments, artisan beer, hidden gardens waiting to be explored and new local friends to show you everything that Panama has to offer are just some of the experiences that you’re bound to have. Sitting in the center of Panama’s cultural and historical district, Las Clementinas offers apartments and studios for seasoned travelers who value comfort and character in their accommodations. Distinct features of the hotel include hardwood floors, colorful tiles, high ceilings and access to the liveliest neighborhood in the whole city.

Calle 11 & Avenida B, Casco Antiguo, Panama City, Panama, Phone: 507-308-6550

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15.La Meridien Panama

La Meridien Panama
© La Meridien Panama

Offering stunning views of the Pacific Ocean and the city’s gorgeous skyline, the La Meridien Panama is a luxurious hotel conveniently located at the end of Panama Bay. Modern and incredibly stylish, the La Meridien inspires visitors to awaken their senses and try out every stimulating experience possible while exploring Panama. The hotel is known for paying incredible detail to attention, the hotel features hydrotherapy facilities, a sauna, whirlpool and more at the Sensory Spa by Clarins. The hotel also has a pool and aqua terrace that overlooks the Panama Bay, a 24-hour fitness facility and a club lounge just to name a few great of their great recreational options.

Calle Uruguay y Balboa Avenue, Panama City, Panama, Phone: 507-297-3200

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16.Novotel Panama City

Novotel Panama City
© Novotel Panama City

Whether you’re traveling for business or pleasure, you can’t go wrong with a stay at the Novotel Panama City Hotel. The Novotel offers comfortable and spacious rooms with king-size beds, a work area for busy travelers and a superb view of the cosmopolitan city that is Panama. Get your daily workouts in at the fitness center before heading to the hotel’s restaurant to savor tasty traditional dishes. The interiors of the hotel are also a feast for the eyes with many works by local artists adorning the hotel walls. Location is equally important in a hotel, which is why the Novotel is conveniently located nearby the Panama Canal, great shopping centers and more.

Calle Josi I. Fabregas y Thais De Pona al lado de Casa de Mano de Piedra Duran 581, Panama City, Panama, Phone: 507-206-8600

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17.Hotels in Panama: American Trade Hotel

Hotels in Panama: American Trade Hotel
© American Trade Hotel

While the American Trade Hotel and isn’t flashy like many of its competitors, the American Trade Hotel is, without a doubt, one of the most popular and memorable luxury boutique hotels to stay at in Panama City’s Casco Viejo neighborhood. The hotel has 50 rooms within a fully restored building originally built in 1917 and is located in the center of a UNESCO World Heritage neighborhood known for its vibrancy and lively community. Every detail in the hotel is well thought out from its Aesop toiletries, to the special hand-woven bathrooms and the stylish interiors. Did we mention the excellent jazz club located in the hotel?

Plaza Herrera, Casco Viejo, Panama, Phone: 507-211-2000

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18.Panama Hotels: Panama Marriott Hotel

Panama Hotels: Panama Marriott Hotel
© Panama Marriott Hotel

Excellence and hospitality are at their finest at the Panama Marriot Hotel. Nestled in the heart of Panama City, the Marriot is popular for being in the center of all the top attractions in the area. For example, the hotel is just a short distance from the Soho Mall, Casco Viejo and the Panama Canal to name a few beloved locations nearby. At the end of a busy day, you can slip into your own personal sanctuary care of the luxurious and comfortable suites that the hotel has to offer. If you want to truly enjoy the relaxation that the hotel can provide, have breakfast in bed while enjoying your favorite movie or TV show on a flat screen TV. Better yet, head over to Corvina Y Caña, he hotel’s in-house restaurant, for an authentic gastronomic tour of Panama’s best eats.

Calle 52 y Ricardo Arias, Area Bancaria, Panama City, Panama, Phone: 507-210-9100

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19.Radisson Decapolis Hotel Panama City

Radisson Decapolis Hotel Panama City
© Radisson Decapolis Hotel Panama City

Experience true Panamanian hospitality first hand when you stay at the Radisson Decapolis Hotel in Panama City. A busy hotel in the downtown area, the Radisson is just a 20-minute drive from the Tocumen International Airport and is a great hotel to consider for business trips and leisure travel alike. For visitors who are eager to explore what the neighborhood has to offer, the Radisson has a walkway that is directly connected to the Multicentro Shopping Mall, which is also home to the Hard Rock Café, a casino and the Aqua Spa. Radisson Decapolis Hotel has 240 rooms and suites, all of which are stylishly decorated and packed with great amenities to make your stay as comfortable as possible.

Avenida Balboa-Multicentro, Panama City, Panama 0833-0293; Phone: 800-052-0129

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20.Dreams Delight Playa Bonita Panama Resort and Spa

Dreams Delight Playa Bonita Panama Resort and Spa
© Dreams Delight Playa Bonita Panama Resort and Spa

Explore and enjoy the beach, rainforest, mountains and city all in one when you book a stay at the Dreams Delight Playa Bonita Panama. As the closest beach to Panama City, the Playa Bonita is an extremely popular beach destination when in the country and its beauty certainly does not disappoint. The Dreams Delight makes a beautiful destination for a romantic getaway or even a memorable vacation with the entire family. Choose from one of the 307 extravagant guest rooms and suites that are housed in 11 seaside towers. Jungle walkways and remarkable views await all eager adventurers too while those who just want to enjoy the hotel can visit the gourmet restaurants, bars and lounges in the compound.

KM 7 Road to Veracruz, Playa Bonita, Panama, Phone: 866-237-3267

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21.Hotels in Panama: Sercotel Panama Princess Hotel

Hotels in Panama: Sercotel Panama Princess Hotel
© Sercotel Panama Princess Hotel

Exuding excellence in every way, the Sercotel Panama Princess Hotel is a 4-star hotel located in the heart of Panama City’s financial district. The hotel is just a stone’s throw from the historic Old Town in the city center and is also a short distance away from the Panama Canal. What’s great about the Sercotel Panama Princess Hotel is that while it’s near much of the action in the city, the immediate vicinity of the hotel provides peace and quiet, so you can be assured of a restful night’s sleep. Other great places to visit nearby include the hotel’s casino, the Amador Causeway, the Bridge of the Americas and the Iglesia del Carmen.

Calle 53 Este Marbella Avenida Stab Sur. Edificio World Trade Center, Panama City, Panama, Phone: 507-309-6900

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22.The Bristol Hotel Panama City

The Bristol Hotel Panama City
© The Bristol Hotel Panama City

If there’s one thing is absolutely certain, it’s that the Bristol Hotel in Panama City has mastered the art of Panamanian hospitality. Apart from the contemporary luxury of the hotel’s accommodations, other elements that make The Bristol an amazing place to stay include gourmet Panamanian cuisine, stunning architecture and timeless designs. All of these features come together to create a one-of-a-kind travel experience characterized by five-star luxury and total sophistication. Rated as of the top ten hotels in Latin America by Conde Nast Traveler, visitors can be certain that the hospitality and amenities will be top notch.

Avenida Aquilino de la Guardia, Panama City, Panama 0835-00257, Phone: 507-264-0000

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23.Torres de Alba Hotel and Suites

Torres de Alba Hotel and Suites
© Torres de Alba Hotel and Suites

There’s no denying that the Tores de Alba Hotel and Suites is one of the top places to stay in Panama City when it comes to location. The hotel is set in the financial district and offers serviced apartments in addition to the usual guest rooms and suites. Truly, staying at the Tores de Alba is a lot like staying in a home away from home as each suite has a living room with a flat-screen TV, cable and a safe. The suite’s kitchen is equally well equipped with a washing machine and much of what you would need in a regular kitchen. If you don’t want to cook your own meals, no problem. Room service is available and there’s also a bar and a restaurant to pay a visit to.

Avenida Eusebio A. Morales, El Cangrejo 0823-04995, Panama City, Phone: 507-300-7130

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24.Panama Resorts: Urraca Private Island

Panama Resorts: Urraca Private Island
© Urraca Private Island

Whether you’re on a romantic weekend getaway or just looking for a fun vacation to take with the family, Urraca Private Island is at your service and ready to provide you with a unique and unforgettable experience in Panama. At Urraca, it’s all about enjoying island lifestyle to the fullest. The accommodations alone reflect that theme as guests can choose between rooms like the Honeymooner’s Hut, Bungalows for Two and Family Bungalows as well. Guests are treated to a pristine and exclusive beach, one of the most exclusive in the Bocas, which is also a gateway to the remarkable underwater paradise surrounding the island. Snorkel the day away or relax on the shore, whatever you want to do, the staff of Urraca will be there to make sure that you enjoy your vacation to the fullest.

Punta Laurel, Panama, Phone: 507-6668-2027

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25.Villa Palma Boutique Hotel

Villa Palma Boutique Hotel
© Villa Palma Boutique Hotel

Just when we thought it was impossible to find any more beautiful places to stay in San Felipe, the Villa Palma Boutique Hotel entered the picture with their uncompromising standards of quality and service. Established in 2014, the Villa Palma Boutique Hotel is a groundbreaking 5-star establishment situated in the old town of Panama City. The hotel features a European style and 14 exclusive rooms that marry elegance, class and extraordinary design in every inch of space. The rooms are undoubtedly luxurious and are quite large. They’re also fully furnished with incredible modern amenities that will make you feel like royalty. Enjoy top notch services like 24-hour reception service, room service, free Wi-Fi, wake-up calls, a great selection of liquor in the mini bar and even access to the high-class Skybar. What more could a frequent traveler ask for?

Casco Antiguo Calle Primera, San Felipe, Panama, Phone: 507-303-1414

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25 Best Panama Hotels & Resorts

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Hotel Riande Granada Urban

Founded in 1969 by Don Ildefonso Riande Peña, the Hotel Riande Granada Urban is one of first hotels that was ever established in Panama. Additionally, it’s largely recognized as being one of the most important hotels in the city. A symbol of Panamanian hospitality, the hotel proudly runs under a family administration and is committed to making sure that every guest is fully satisfied with the Hotel Riande’s service. Rooms available are the standard, superior, club level, executive, junior suite and presidential suites. Meanwhile, paces in the hotel to visit and spend some time in are the Solo Restaurant, the Stay bar, the Biergarten and the Bierpub.

Calle Eusebio A. Morales, El Cangrejo, Panama, Phone: 507-204-4444

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