With the Mississippi, the Columbia, and more, America is home to some enormous and iconic rivers that have played key roles in the development of the nation. Each river has its own stories to tell and stunning scenery to offer, and one of the best ways to enjoy the rivers of America is by taking a river cruise. With cruise lines like American Queen Steamboat Company and American Cruise Lines offering multiple routes and experiences at great prices, there’s never been a better time to book a USA river cruise. Read on to learn about a few of the best river cruises you can choose.

1.American Queen Steamboat Company - 8 Night Mark Twain's Mississippi - American Queen

American Queen Steamboat Company - 8 Night Mark Twain's Mississippi - American Queen
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One of the most iconic rivers in the United States is undoubtedly the Mississippi, and this ‘8 Night Mark Twain's Mississippi’ cruise from the American Queen Steamboat Company is an awesome way to explore this stunning river like never before. With rooms available for around $300 per night and plenty of different room types to choose from, this is a fully flexible cruise that can work with different budgets and desires.

This cruise lets you climb aboard the wonderful American Queen. Unlike any other cruise ship on Earth, the American Queen was designed to look just like the old Mississippi riverboats, offering a really authentic Mississippi River cruise experience. The ship has been lovingly crafted and decorated with Victorian-era influences and authentic furnishings. It even features its own saloon, where live music is played regularly, and also offers multiple dining options and plenty of other features.

This cruise begins in the Missouri city of St Louis before heading off along the Mississippi through multiple states including Iowa, Wisconsin and Minnesota. You’ll be able to admire the changing scenery and various landmarks along the flow of the Mississippi, while also getting a chance to explore the various ports of call like Hannibal in Missouri, Clinton in Iowa, La Crosse in Wisconsin, and Minneapolis, one of the Twin Cities of Minnesota. It’s a great American river cruise to choose and really lets you experience one of the country’s most significant waterways in a way you never imagined possible.

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2.American Queen Steamboat Company - 8 Night Welcome to the Magnificent Pacific Northwest - American Empress

American Queen Steamboat Company - 8 Night Welcome to the Magnificent Pacific Northwest - American Empress
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Head off on an amazing cruise along the Columbia River with this '8 Night Welcome to the Magnificent Pacific Northwest' cruise from the American Queen Steamboat Company. With prices starting at around $2,000, this luxury American river cruise is an amazing option for the whole family to enjoy, while also being well-suited for romantic getaways and more.

This cruise lets you travel on board the American Empress, one of the best river cruise ships anywhere in the world. Beautifully decorated both inside and outside, this ship offers total luxury and opulence throughout and was designed as the perfect 'home away from home' for every guest. Regionally-inspired menu and meals will be served on the ship, which also offers Broadway-style live shows and entertainment in various forms. The full concierge service will help to organize guided tours and activities at the various ports of call, and you'll find that the Empress is able to make every aspect of your trip as exciting and memorable as possible.

This Columbia River cruise begins in Vancouver, Washington State and sets off along the iconic river, stopping first at Astoria in Oregon. There, you can visit the Columbia River Maritime Museum or ride the Astoria Riverfront Trolley for another angle on the Columbia River. Next, you'll spend some time simply cruising along the Columbia before arriving at The Dalles, Oregon, a highly picturesque location for people of all ages to enjoy. The next stop is at the little city of Stevenson, WA, where you'll find some great local golf courses and nature trails. Finally, the cruise will make its last stop at Portland, Oregon.

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3.American Cruise Lines - 10 Night Ohio River Cruise - Queen of the Mississippi

American Cruise Lines - 10 Night Ohio River Cruise - Queen of the Mississippi
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For another kind of river cruise in the United States, choose the '10 Night Ohio River Cruise' from American Cruise Lines. Available at some great prices, with multiple sail dates lined up for the coming years, this small ship cruise lets you enjoy an authentic river cruise experience on board a real riverboat, the Queen of the Mississippi.

This ship has been designed with authenticity and comfort in mind. You'll feel like you're stepping back in time as you first climb aboard and admire the intricate detailing on the woodwork and the authentic designs and furnishings found all over the vessel, but you'll also be able to enjoy all the comforts and convenience of a contemporary cruise ship, including high speed Wi-Fi, lots of lounges, a putting green, a grand dining room, a Mark Twain library, afternoon tea, live entertainment in the evenings, on-board experts to help you learn more about the Ohio River and the various locations you'll be visiting, and more.

This 10 night cruise sets off from the city of St Louis in Missouri and travels through multiple states along its unique, beautiful journey. You'll be able to stop off at various cities and locations along the way including Paducah and Louisville in Kentucky, Cincinnati and Marietta in Ohio, and Pittsburgh in Pennsylvania. Each stop is different, having its own unique charms and experiences to enjoy, making this cruise a truly one of a kind experience.

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3 Best River Cruises in USA